The Cleveland Clinic was established in 1921 by three WWI surgeons, George Washington Crile (pictured above), Frank Bunts, and William Lower. They invited a local internist, John Phillips to join the project. The concept of group practice was all but unheard of at the time. Only the Mayo Clinic in the United States operated on such a model.
The Cleveland Clinic was the site of one of the city's most spectacular disasters in 1929 when a fire in the basement of the hospital, set off by highly flamable X-Ray film, ignited the building, claiming 123 lives, including that of founder John Phillips.
The Clinic continued to grow despite the Great Depression and WWII, establishing itself as one of the primary cardiac care hospitals in the world. The Cleveland Clinic has been responsible for many firsts in health care, including:
- first successful larynx transplant
- first coronary bypass surgery (CABG) by Rene Favaloro in 1967
- discovery of first gene linked to familial coronary artery disease
- identification of carpal tunnel syndrome
- first minimally invasive aortic valve surgery


